Tables of Rules

INTEGRASE INHIBITOR
Nucleoside and Nucleotide reverse transcriptase inhibitors Protease inhibitors

Non-Nucleoside reverse transcriptase inhibitors Fusion inhibitors

HIV - 2 Integrase inhibitors

  Mutations associated with resistance Mutations associated with "possible resistance"
RAL
 T66K [10]
E92Q [1, 2]
F121Y [10]
G140A/S [7]
Y143C/G/H/R/S [1, 3, 4, 5, 9]
Q148E/G/H/K/R [1, 2]
V151L [10]
N155H/S/T [1, 2, 10]
E157Q [2]
At least 3 mutations among : V72I, L74M, T97A, V151I, G163R, S230R [8, 10]
EVG T66I/A/K [6]
E92Q [6]
F121Y [10]
E138K
G140C/S
P145S [10]
S147G
Q148H/R/K [6]
V151L [10]
N155H/S/T [6, 10]
DTG V151L [10]
S153Y
T66K + L74M
E92Q + N155H
E138A/K + Q148H/K/R
G140C/S + Q148H/K/R
Q148R + N155H		 T66K [10]
S153F

RAL: raltegravir, EVG: elvitegravir, DTG: dolutegravir .

References